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Toxicology in the 21st Century

21st Century Toxicology: A new Vision and a new Testing Strategy for toxicity assessment!

A change always involves a pivotal event that builds on the past and opens the door to a new era. We can cite examples of pivotal events in science such as the discovery of penicillin, the elucidation of the DNA double helix, the development of computers. All of these events were marked by inauspicious beginnings followed by advances unheralded for years, but which ultimately resulted in a…

Safety Assessment of Cosmetic Ingredients and Products

Safety Assessment of Cosmetic Ingredients and Products

Cosmetics in Europe are regulated by Legislation (EC) No. 1223/2009, which requires that cosmetic products must be safe for use before being placed on the market. This must be done through a safety assessment contained in a single product dossier (PIF, Product Information File), which must be prepared by a qualified and certified safety assessor. Product evaluation…

Rheology-Rheometry

Rheology and Rheometry applied to Cosmetics

Rheology is the study of the deformation and flow (flow) of materials. Rheometry, on the other hand, would measure the rheological properties of materials. It is a branch of Physics study, related to materials and industries as diverse as food, civil construction, petrochemicals, oil well drilling engineering, plastics, paints, pharmaceuticals, and cosmetics, to name a few. The rheological characterization of emulsions, suspensions, and emulsion-suspensions (a filter…

The Jabuticaba

The jaboticabeira is typically Brazilian, belonging to the Angiosperma group and the Myrtaceae family. The Atlantic Forest holds 85% of the total described species in its associated ecosystems. In ethnobotanical studies in the Atlantic Forest of Bahia, myrtaceous species are among the four most important families in terms of traditional use value. Among the fruit species in this family, the jabuticabeira Plinia peruviana (Poir) Govaerts stands out. To the…

Cellular aging

Senescent cells under the microscope, with the blue regions indicating an increase in the production of the CD36 gene. Darleny Lizardo/Alan Siegel/University at Buffalo North Campus Confocal Imaging Facility. https://newatlas.com/cell-senescence-gene-found/55195/ Aging, as a phenomenon in the lifespan of organisms, has intrigued humanity since time immemorial. Why and how is it that, having reached vigorous adulthood, all functions must undergo decay? The duration of this…

The benefits of Cannabis in cosmetic products

In the Cosmetics area, there is a profound movement to use Cannabis bioactives, known as cannabinoids, in various applications and benefits for the skin. Cannabis contains hundreds of bioactives, however the most important of them is Cannabidiol (CBD) and can be found as an oily extract, which is also free, or with minimal portions of Tetrahydrocannabinol (THC), the psychotropic portion of the plant. In several…

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